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NEPA21 / CUY21 Applications

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[Brain] Electroporation-mediated gene transfer in the adult rat brain

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Figure A: EGFP expression in the medial preoptic nuclei of a female rat examined 4 days after bilateral electroporation at 10 weeks of age.

(An asterisk indicates the trace of the positioning of the electrode)

Figure B: EGEP-positive cells (high magnification of Fig. A using a 60x objective lens)  EGFP fluorescent signals are observed in the perikarya.

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Figure C: Estrogen receptor α immunoreactivity in the medial preoptic nuclei and the periventricular nuclei of an adult female rat.

3V: third ventricle

Figure D: Estrogen receptor α-positive cells (high magnification of Fig. C using a 60x objective lens).  Estrogen receptor α immunoreactivity is prominent in the nuclei.

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Center for Advanced Oral Medicine, Hokkaido University Hospital; Tetsuo Shirakawa