Epidermis-Targeted Gene Transfer Using In Vivo Electroporation

Epidermis-Targeted Gene Transfer Using In Vivo Electroporation

NEPA21 / CUY21 Applications.

[Skin] Epidermis-Targeted Gene Transfer Using In Vivo Electroporation

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CUY663-5X10 Tweezers Electrode with Variable Gap 3 Needle Fork and Stainless Steel Rectangle Plate

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(1) Tweezers with Variable Gap 3 Needle Fork & Stainless Steel Rectangle Plate Electrode, 5mm x 10mm (CUY663-5X10: NEPA GENE)

(2) Pulse generator (CUY21 EDIT Square Wave  Electroporator: NEPA GENE)


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ß-Galactosidase expression on d 1 (A) and d 7 (B) after the pCAGGS-lacZ transfer with electroporation at 18V.

ß-Galactosidase was expressed in the upper most cell layers (horny, granular, and prickle cell layers) of the epidermis on d 1 (A), and in the subcutaneous muscle layer on d 7 (B).

Magnification: (A) x 250, (B) x 70

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Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences; Hiroki Maruyama

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