The
SONIDEL SP100
Sonoporation Platform

Is optimised for the following applications:

• Gene Transfection/Sonoporation
  • Non-invasive stimulation of gene transfer
  • Efficient gene/nucleic acid transfer
  • In vivo and in vitro applications
  • Compatible for use with plasmids and minicircle DNA
  • Precludes viral transfection and associated challenges
  • Reduced contamination risk
  • Minimal impact on cell/tissue viability
  • Compatible range of accessories including microbubble preparations (MB101) and Positive Control Kit (STK10)
  • Photographic Results

• Drug Targeting – enhancing Cancer Chemotherapeutics
  • Exploiting ultrasound-mediated transient cell-membrane permeabilisation
  • Exploiting ultrasound-mediated tissue dispersion (recently demonstrated)
  • Proven to enhance the cytotoxicity of cancer chemotherapeutic agents in vitro and in vivo
  • Site-specific targeting of cytotoxic effects by application of ultrasound to the target site
  • Non-invasive stimulation of targeted effects
  • Publications

• Sonodynamic Therapy for Cancer
  • SP100 Platform is adaped for activation of sonodynamic agents
  • Site specific targeted cytotoxic effects for the treatment of solid tumors
  • Non-invasive activation of the sonodynamic agents
  • Non-invasive targeting of cytotoxic effects Sonodynamic Therapy
  • Publications

SONIDEL SP100 Sonoporator …………………………………………….SONIDEL MB101 Microbubble

SONIDEL STK10 Transfection Kit ………………………………………Full Sonoporation Publication List